Unlock Precision with AxisPharm’s High-Performance LC-MS Services
Experience Unmatched Excellence in Liquid Chromatography-Mass Spectrometry
AxisPharm offers premium LC-MS (Liquid Chromatography-Mass Spectrometry) services, combining high-performance liquid chromatography (HPLC) with advanced tandem mass spectrometry for precise and reliable analysis. Our expert team and state-of-the-art facilities deliver tailored solutions that meet the demanding needs of scientific and pharmaceutical research.
Why Choose AxisPharm’s LC-MS Services?
- Advanced LC-MS Capabilities
- Comprehensive Equipment: Our lab features Single-Quadruple, Triple-Quadruple, Ion Trap, TOF, and Q-TOF systems, supporting a wide range of analytical techniques.
- Versatile Ionization Sources: We utilize Electro-Spray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI), and more to detect diverse molecules, even those challenging to identify.
- High-Resolution Analytical Techniques
- Precision and Sensitivity: Integrated with PDA, ELSD, CAD, and FLD detectors, our systems provide accurate compound characterization and quantification.
- High-Performance LC Separation: Our advanced LC separation capabilities use optimized gradient runs on a 2.1×50 mm C18 column, delivering rapid and reliable data in just 7 minutes.
- Mass Analysis Capabilities
- Tandem Mass Spectrometry: Our tandem MS systems enable detailed mass analysis, enhancing the accuracy of compound identification and structural elucidation.
- Tailored Analytical Solutions
- Custom Method Development: We adapt to your specific needs, supporting custom methods with specialized columns and solvents.
- Detailed Reporting: Receive in-depth reports with UV traces, Total Ion Current (TIC) traces, and spectra for a comprehensive overview of your analysis.
Our LC-MS Analysis Process
- Sample Preparation: Extract and prepare samples, including plasma, urine, and tissue, using protein precipitation or solid-phase extraction.
- Chromatographic Separation: Perform LC separation of analytes based on physicochemical properties.
- Ionization: Convert molecules into gas-phase ions using ESI or APCI techniques.
- Mass Analysis: Separate ions by mass-to-charge ratio using our advanced mass spectrometry systems.
- Detection and Quantification: Precisely detect and quantify ions to determine analyte concentrations.
- Calibration Curve: Construct calibration curves for accurate quantification.
- Data Analysis: Utilize specialized software to process and ensure data accuracy.
- Validation: Validate methods for precision, sensitivity, and specificity.
Applications and Benefits
- Pharmaceutical Research: Accelerate drug development with high-performance LC-MS for compound identification and quantification.
- Clinical Diagnostics: Enhance diagnostic accuracy with high-sensitivity biomarker detection.
- Toxicology Studies: Assess drug metabolism and toxicity with detailed metabolic profiling.
Get Started with AxisPharm
Maximize your research capabilities with AxisPharm’s advanced LC-MS services. Contact us today to discuss your project, request a quote, or learn how our expertise can support your scientific goals.
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For FDA Bioanalytical Method Validation Guidance, please check.
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