Bioconjugation Analytical Method Development with AxisPharm
Overview
AxisPharm offers complete analytical method development for bioconjugation projects. Our skilled team uses advanced tools to create accurate tests, ensuring bioconjugates meet high standards for therapies and diagnostics.
Analytical Capabilities
AxisPharm provides a range of techniques to analyze bioconjugates:
- Wet Chemistry: Basic tests for chemical stability.
- Chromatography (HPLC, GC, UPLC): Checks purity and separation.
- Electrophoresis: Confirms molecular weight and purity.
- Spectroscopy (UV-Vis): Quick absorbance checks.
- Binding Assays (ELISA): Tests how well bioconjugates bind.
- Water Content (Karl Fisher): Measures moisture levels.
- Endotoxin Testing (LAL): Ensures biocompatibility.
- Spectrometry (NMR, LC-MS, MALDI-TOF): Provides structural details.
Method Development and Optimization
Our process includes selecting, refining, and validating methods to meet project needs:
- Sensitivity and Specificity: Detects targets accurately.
- Linearity and Range: Ensures accurate results at different levels.
- Stability Testing: Monitors product shelf-life.
Bioconjugation Services
AxisPharm also offers flexible, affordable bioconjugation services:
- Antibody-Drug and Antibody-Oligonucleotide Conjugates
- Protein-Drug, Fluorophore, and Biotin Conjugation
- Polymer–Drug and Polymer-Drug-Target Ligand Conjugation
- PEGylation and Cross-Linking for added stability
- Cysteine and Lysine-Based Conjugations
- Thio-Engineered Antibody, Carbohydrate, and Unnatural Amino Acid Conjugations
Quality and Compliance
AxisPharm follows strict standards to ensure safety and consistency:
- GMP Compliance: For clinical-grade products.
- Quality Control: Routine testing for reliability.
- Documentation: Meets regulatory standards.
Conclusion
AxisPharm’s expertise in method development and bioconjugation provides high-quality solutions. Our services ensure stable, effective bioconjugates for successful therapeutic and diagnostic use.